BGC > Product Search > 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine | 1346547-00-9

Molecular Formula: C20H19FN4O2S
Molecular Weight: 398.4538632

Molecular Formula: C20H19FN4O2S
Molecular Weight: 398.4538632

Description :
GSK583 is a selective receptor-interacting serine/threonine-protein kinase 2 (RIP2 Kinase) inhibitor and the RIP2K binding IC50 is 5 nM. GSK583 can inhibit both TNF-α and IL-6 production with an IC50 value of 200 nM in an ex vivo human translational model.

• Molecular Weight :398.46
• Purity :98%

Molecular Formula :
C20H19FN4O2S
Canonical SMILES :
O=S(C1=CC=C(N=CC=C2NC3=NNC4=C3C=C(F)C=C4)C2=C1)(C(C)(C)C)=O
InChI :
1S/C20H19FN4O2S/c1-20(2,3)28(26,27)13-5-7-16-14(11-13)17(8-9-22-16)23-19-15-10-12(21)4-6-18(15)24-25-19/h4-11H,1-3H3,(H2,22,23,24,25)
InChIKey :
XLOGLWKOHPIJLV-UHFFFAOYSA-N
Solubility :
DMSO ≥ 37 mg/mL
Appearance :
Powder
Storage : -20°C Freezer
Synonyms :
GSK583; GSK 583; GSK-583. 6‑(tert-Butylsulfonyl)‑N‑(5-fluoro‑1H‑indazol-3-yl)quinolin-4-amine

More details are to be found here

Purity : 98%
Smile code : FC1=CC2=C(NN=C2NC3=CC=NC4=CC=C(S(=O)(C(C)(C)C)=O)C=C34)C=C1
MDL Number : MFCD30343846
MolFormula : C20H19FN4O2S
MolWeight : 398.4539
Available in stock : 2.246

More details are to be found here

Smile code:
FC1=CC2=C(NN=C2NC3=CC=NC4=CC=C(S(=O)(C(C)(C)C)=O)C=C34)C=C1
MDL Number:
MFCD30343846
Purity :
98%
Available in stock:
12.14 g

More details are to be found here