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Suppliers for
Lonafarnib
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Properties | | CAS |
193275-84-2 | | Formula |
C27H31Br2ClN4O2 |
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7 Registered suppliers
| Appearance | white powder
| | Purity (gc area %) | ≥ 98.5%
| | H NMR | Conforms to structure |
| Appearance | white powder
| | Purity (gc area %) | ≥ 98.5%
| | H NMR | Conforms to structure |
Molecular Formula: C27H31Br2ClN4O2 Molecular Weight: 638.82
More details are to be found here
Molecular Formula: C27H31Br2ClN4O2 Molecular Weight: 638.82164
More details are to be found here
Molecular Formula: C27H31Br2ClN4O2 Molecular Weight: 638.82164
More details are to be found here
Description : Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. - Molecular Weight :638.829
- Melting Point :150-152°C
- Purity :> 95%
Molecular Formula : C27H31Br2ClN4O2 Canonical SMILES : C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N
InChI :
InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1
InChIKey :
DHMTURDWPRKSOA-RUZDIDTESA-N
Solubility :
~3mg/ml
Appearance :
white solid powder
Application :
Enzyme Inhibitors
Synonyms :
SCH 66336; SCH-66336; SCH66336; Sarasar
More details are to be found here
Description : Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic tricyclic derivative of carboxamide with antineoplastic properties. Lonarfanib binds to and inhibits farnesyl transferase, an enzyme involved in the post-translational modification and activation of Ras proteins. Ras proteins participate in numerous signalling pathways (proliferation, cytoskeletal organization), and play an important role in oncogenesis. Mutated ras proteins have been found in a wide range of human cancers. - Molecular Weight :638.829
- Melting Point :150-152°C
- Purity :> 95%
Molecular Formula : C27H31Br2ClN4O2 Canonical SMILES : C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(C=C(C=C4CCC5=CC(=CN=C35)Br)Cl)Br)C(=O)N
InChI :
InChI=1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11H2,(H2,31,36)/t25-/m1/s1
InChIKey :
DHMTURDWPRKSOA-RUZDIDTESA-N
Solubility :
~3mg/ml
Appearance :
white solid powder
Application :
Enzyme Inhibitors
Synonyms :
SCH 66336; SCH-66336; SCH66336; Sarasar
More details are to be found here
Detailed information on the suppliers of
Lonafarnib |
Properties:
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Last update 2024-05-23
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