BGC > Product Search > (2S)-N1-[4-methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidinedicarboxamide | 1217486-61-7

Molecular Formula: C19H22F3N5O2S
Molecular Weight: 441.4704896
HS Code: 29341000

Molecular Formula: C19H22F3N5O2S
Molecular Weight: 441.4704896
HS Code: 29341000

Description :
Alpelisib, also known as BLY719, is an orally bioavailable phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplastic activity. PI3K inhibitor BYL719 specifically inhibits PIK3 in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis. Dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents.

• Molecular Weight :441.473

Molecular Formula :
C19H22F3N5O2S
Canonical SMILES :
CC1=C(SC(=N1)NC(=O)N2CCCC2C(=O)N)C3=CC(=NC=C3)C(C)(C)C(F)(F)F
InChI :
InChI=1S/C19H22F3N5O2S/c1-10-14(11-6-7-24-13(9-11)18(2,3)19(20,21)22)30-16(25-10)26-17(29)27-8-4-5-12(27)15(23)28/h6-7,9,12H,4-5,8H2,1-3H3,(H2,23,28)(H,25,26,29)/t12-/m0/s1
InChIKey :
STUWGJZDJHPWGZ-LBPRGKRZSA-N
Appearance :
white solid powder
Synonyms :
BYL-719; BYL719; BYL 719; Alpelisib;

More details are to be found here

Purity : 99%
Smile code : O=C(N1[C@H](C(N)=O)CCC1)NC2=NC(C)=C(C3=CC(C(C)(C)C(F)(F)F)=NC=C3)S2
MDL Number : MFCD22417085
MolFormula : C19H22F3N5O2S
MolWeight : 441.4705
Available in stock : 6.951

More details are to be found here

Smile code:
O=C(N1[C@H](C(N)=O)CCC1)NC2=NC(C)=C(C3=CC(C(C)(C)C(F)(F)F)=NC=C3)S2
MDL Number:
MFCD22417085
Purity :
99%
Available in stock:
16.515 g

More details are to be found here