Description :
AWD 131-138 is a partial agonist of GABAA receptor with low affinity for the benzodiazepine binding site. AWD 131-138 exhibits potent anticonvulsant and anxiolytic properties in rodent models. It is used as an antiepileptic drug for the treatment of canine idiopathic epilepsy.
- Molecular Weight :279.724
Molecular Formula :
C13H14ClN3O2
Canonical SMILES :
C1COCCN1C2=NC(=O)N(C2)C3=CC=C(C=C3)Cl
InChI :
InChI=1S/C13H14ClN3O2/c14-10-1-3-11(4-2-10)17-9-12(15-13(17)18)16-5-7-19-8-6-16/h1-4H,5-9H2
InChIKey :
IQHYCZKIFIHTAI-UHFFFAOYSA-N
Synonyms :
AWD 131-138; AWD-131-138; AWD131-138; AWD 131138; Imepitoin; 3-(4-chlorophenyl)-5-morpholin-4-yl-4H-imidazol-2-one
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