BGC > Product Search > 7-Bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxy-2-piperidinyl]-2-oxopropyl]-4-quinazolinone | 55837-20-2

Molecular Formula: C16H17BrClN3O3
Molecular Weight: 414.68

Molecular Formula: C16H17BrClN3O3
Molecular Weight: 414.68

Molecular Formula: C16H17BrClN3O3
Molecular Weight: 414.68

Molecular Formula: C16H17BrClN3O3
Molecular Weight: 414.68

Description :
Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities. Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor cell growth. These effects appear to be due to halofuginone-mediated inhibition of the collagen type I and MMP-2 promoters. Collagen type I and MMP-2 play important roles in fibro-proliferative diseases.

• Molecular Weight :414.684
• Boiling Point :595.8±60.0 °C at 760 mmHg
• Melting Point :> 150°C
• Purity :> 95%

Molecular Formula :
C16H17BrClN3O3
Canonical SMILES :
C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O
InChI :
InChI=1S/C16H17BrClN3O3/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14/h5-6,8,14-15,19,23H,1-4,7H2/t14-,15+/m0/s1
InChIKey :
LVASCWIMLIKXLA-LSDHHAIUSA-N
Application :
semisynthetic quinazolinone alkaloid anticoccidial
Storage : -20°C
Synonyms :
Halofuginone; Tempostatin; RU 19110; RU19110; RU-19110

More details are to be found here

Purity : 98%
Smile code : O=C1N(CC(C[C@H]2NCCC[C@@H]2O)=O)C=NC3=C1C=C(Cl)C(Br)=C3
MDL Number : MFCD09834143
MolFormula : C16H17BrClN3O3
MolWeight : 414.6815
Available in stock : 0.002

More details are to be found here

Purity : 98%
Smile code : O=C1N(CC(C[C@H]2NCCC[C@@H]2O)=O)C=NC3=C1C=C(Cl)C(Br)=C3
MDL Number : MFCD09834143
MolFormula : C16H17BrClN3O3
MolWeight : 414.6815
Available in stock : 0.002

More details are to be found here