BGC > Produktsuche > Sofosbuvir

Molecular Formula: C22H29FN3O9P
Molecular Weight: 529.4525242
HS Code: 29339900

Drug Category: HEPATITIS C
Site: Virupaksha Organics Ltd

Assay:99.0%min

Description:
Sofosbuvir is a prodrug that is metabolized to the active antiviral agent 2'-deoxy-2'-α-fluoro-β-C-methyluridine-5'-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled sofosbuvir as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase.

• Molecular Weight:529.45
• Purity:>98%

Molecular Formula:
C22H29FN3O9P
Canonical SMILES:
CC(C)OC(=O)C(C)NP(=O)(OCC1C(C(C(O1)N2C=CC(=O)NC2=O)(C)F)O)OC3=CC=CC=C3
InChI:
InChI=1S/C22H29FN3O9P/c1-13(2)33-19(29)14(3)25-36(31,35-15-8-6-5-7-9-15)32-12-16-18(28)22(4,23)20(34-16)26-11-10-17(27)24-21(26)30/h5-11,13-14,16,18,20,28H,12H2,1-4H3,(H,25,31)(H,24,27,30)/t14-,16+,18+,20+,22+,36-/m0/s1
InChIKey:
TTZHDVOVKQGIBA-IQWMDFIBSA-N
Solubility:
Soluble in DMF, DMSO, Ethanol, PBS
Appearance:
White Solid
Application:
Antiviral Agents
Storage: Store at -20°C
Synonyms:
PSI-7977; PSI 7977; PSI7977; GS7977; GS-7977; GS 7977; Sovaldi; N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine, 1-methylethyl ester; Hepcinat; Hepcvir; Resof; SoviHep